KINOMEscan - High-Throughtput Kinase Selectivity Profiling

The Industry's Most Comprehensive Kinase Profiling Service

KINOMEscan™ is an innovative, high-throughput method for screening small molecule compounds against large numbers of human kinases. By providing a fast, accurate, uniform and quantitative kinase profile that details how well each compound binds to both intended and unintended targets, KINOMEscan™ transforms the promiscuity of kinase inhibitors into a discovery advantage.

The KINOMEscan™ Advantage

• Fast - Two-week turnaround
• Accurate - Compounds tested under uniform conditions
• Economical - Most screens delivered for under $10 per kinase per compound
• Consistent - Outstanding data reliability
• Confidential - All data blinded and protected
• Comprehensive study report - view sample primary or K_d data reports
• TREEspot Data Visualization Tool

New & Enhanced Kinase Panel: 442 Kinase Assays KINOMEscan announces the expansion of its kinase assay panel with the release of almost fifty new and enhanced kinase assays. As a leading profiling service provider with the industry's most comprehensive panel of kinase assays, KINOMEscan continues to redefine the standard in high-throughput selectivity and off-target profiling. View our new assays and see what you are missing!

New Kinase Panel Highlights:

• MTOR, LRRK2, LRRK2(G2019S), CDK4-cyclinD1, CDK4-cyclinD3
• Three pathogen kinases including M. tuberculosis and P. falciparum
• New lipid, tyrosine, and mutant kinase assays
• scanMODE activated/non-activated assay pairs to elucidate compound binding mode.

Kinase Screening Services Available

scanMAX (442): Best choice for drug discovery and compound optimization Definitive set of 442 kinases - the largest panel commercially available - covering all major kinase groups.

scanEDGE (96): An economical approach to surveying the human kinome Contains a set of 96 kinases distributed throughout the kinome.

scanLIPID (20): The largest commercial panel of human lipid kinases. Includes PIK3, PIK4, and PIP lipid kinase families.

scanTK (127): The world's most complete collection of tyrosine kinases.

scanELECT (1-442): Ultimate flexibility for custom applications An a-la-carte approach to exploring kinases of interest. Choose only the kinases you want.

NEW! scanMODE (12): Employs activated/non-activated assay pairs to elucidate compound binding mode. An ideal tool for understanding how kinase phosphorylation state affects inhibitor affinity.

KdELECT: Quantitative affinity measurement (11-point dose-response curve, performed in duplicate) can be determined for any kinase/compound combination. View sample report. [get more information]

Library Screening and Annotation: Get more from your compound libraries Rapidly and inexpensively screen hundreds or thousands of compounds against any KINOMEscan kinase panel. [get more information]