scanUNIQUE Delta Set CE

158 Kinases You Can’t Get From The Next Leading Provider

When it comes to kinase selectivity and off-target profiling, kinase panel size matters! Larger panels provide not only a better measure of compound selectivity, but a more comprehensive view of potential off-target activity that smaller panels may overlook

See for yourself how KINOMEscan compares to the competition using our scanUNIQUE Delta Set panels, or contact us to receive more information about the assays missing in your current solution provider's portfolio. Then request a quote to see what you're missing!

 






Panel Highlights and Benefits

  • 158 kinases not available from the next leading provider
  • Affords a comprehensive view of potential off-target activity that smaller panels may overlook
  • Avoid costly decisions or even lost opportunities due to incomplete data

 

Delta Set Ce
Red circles represent unique KINOMEscan™ kinases not currently available from the next leading provider.

Case Study: Assessing Compound Selectivity & Potency Across Delta Set Ce Assays

 

Sunitinib


Sunitinib

Erlotinib


Erlotinib

Dasatinib


Dasatinib
Kd values < 3 μM for three FDA-approved kinase inhibitors across the 158 kinases not available from the next leading provider

 

scanUNIQUE™, Delta Set Ce 158 Kinases
AAK1ACVR1ACVR2AACVR2B
ACVRL1ADCK3ADCK4AMPK-alpha1
AMPK-alpha2ANKK1ASK2BIKE
BMPR1BBMPR2BRSK2BUB1
CAMK1GCAMK2BCAMK2DCAMKK1
CAMKK2CASKCDC2L1CDC2L2
CDC2L5CDK11CDKL1CDKL2
CDKL3CDKL5CLK3CLK4
CSNK1A1LCSNK1DCSNK1G1CSNK1G2
CSNK1G3CSNK2A2DAPK3DCAMKL3
DDR1DMPKDMPK2DRAK2
DYRK1BEIF2AK1EPHB6ERBB3
ERK3ERK4ERK8ERN1
GAKGCN2(Kin.Dom.2,S808G)GRK1GRK4
GRK7HASPINHIPK1HPK1
HUNKICKIRAK3LATS1
LATS2LIMK2LKB1LOK
LZKMAKMAP3K1MAP3K15
MAP3K2MAP4K3MAP4K5MAST1
MEK2MEK3MEK4MKK7
MLCKMLK3MRCKBMYLK2
MYLK4MYO3AMYO3BNDR2
NEK11NEK3NEK5NEK9
NLKOSR1PAK3PAK6
PAK7PCTK2PCTK3PFTAIRE2
PFTK1PIK3C2BPIK3C2GPIK3CA
PIK3CBPIK3CDPIK3CGPIK4CB
PIM3PIP5K1APIP5K1CPIP5K2B
PIP5K2CPKAC-betaPRP4QSK
RIOK1RIOK2RIOK3RIPK1
RIPK4RIPK5RSK4(Kin.Dom.1-N-terminal)RSK4(Kin.Dom.2-C-terminal)
SBK1SgK110SIK2SLK
SNARKSNRKSRPK1SRPK2
SRPK3STK16STK35STK36
STK39TAOK1TAOK3TESK1
TGFBR1TGFBR2TIE1TLK1
TLK2TNIKTNNI3KTRPM6
ULK3VRK2WEE2WNK1
YANK1YANK2YANK3YSK1
YSK4ZAK