scanUNIQUE Delta Set I

130 Kinases You Can’t Get From The Next Leading Provider

When it comes to kinase selectivity and off-target profiling, kinase panel size matters! Larger panels provide not only a better measure of compound selectivity, but a more comprehensive view of potential off-target activity that smaller panels may overlook.

See for yourself how KINOMEscan compares to the competition using our scanUNIQUE Delta Set panels, or contact us to receive more information about the assays missing in your current solution provider's portfolio. Then request a quote to see what you're missing!
 




Panel Highlights and Benefits

  • 130 kinases not available from the next leading provider
  • Affords a comprehensive view of potential off-target activity that smaller panels may overlook
  • Avoid costly decisions or even lost opportunities due to incomplete data

 

Delta Set I
Red circles represent unique KINOMEscan™ kinases not currently available from the next leading provider.

Case Study: Assessing Compound Selectivity & Potency Across Delta Set I Assays

 

Sunitinib


Sunitinib

Erlotinib


Erlotinib

Dasatinib


Dasatinib
Kd values < 3 µM for three FDA-approved kinase inhibitors across the 130 kinases not available from the next leading provider.

 

scanUNIQUE™, Delta Set I - 130 Kinases
AAK1ACVR2AACVRL1ADCK3ADCK4ALK
ANKK1ASK2BIKEBMPR1BBMPR2BRSK2
BUB1CAMK1GCAMK2GCASKCDC2L1CDC2L2
CDC2L5CDK11CDK3CDK4-cyclinD1CDKL1CDKL2
CDKL3CDKL5CITCSNK1A1LDAPK2DCAMKL1
DCAMKL3DLKDMPK2DRAK2DYRK2EIF2AK1
EPHA6EPHB6ERBB3ERK3ERK4ERK5
ERK8ERN1GAKGCN2(Kin.Dom.2,S808G)GRK1HPK1
HUNKICKIRAK3LATS1LATS2LKB1
LOKLZKMAKMAP3K1MAP3K15MAP3K4
MAP4K3MAST1MEK4MEK5MKK7MYLK4
MYO3AMYO3BNDR1NDR2NEK11NEK3
NEK5NIM1OSR1PCTK1PCTK2PCTK3
PDPK1PFTAIRE2PFTK1PIK3C2GPIK3CBPIM3
PIP5K1APIP5K1CPIP5K2BPIP5K2CPKAC-betaPKMYT1
PKN2PLK4PRKRPRP4QSKRIOK1
RIOK2RIOK3RIPK1RIPK4RIPK5SBK1
SgK110SIKSNARKSNRKSTK35STK36
STK39TAOK1TESK1TGFBR2TIE1TLK1
TLK2TNIKTNK1TNNI3KTRPM6ULK1
ULK2ULK3VRK2WEE2WNK1WNK3
YANK1YANK2YANK3YSK4