scanUNIQUE Delta Set M

174 Kinases You Can’t Get From The Next Leading Provider

When it comes to kinase selectivity and off-target profiling, kinase panel size matters! Larger panels provide not only a better measure of compound selectivity, but a more comprehensive view of potential off-target activity that smaller panels may overlook.

See for yourself how KINOMEscan compares to the competition using our scanUNIQUE Delta Set panels, or contact us to receive more information about the assays missing in your current solution provider's portfolio. Then request a quote to see what you're missing!
 

Panel Highlights and Benefits

  • 174 kinases not available from the next leading provider
  • Affords a comprehensive view of potential off-target activity that smaller panels may overlook
  • Avoid costly decisions or even lost opportunities due to incomplete data

 

Delta Set M
Red circles represent unique KINOMEscan™ kinases not currently available from the next leading provider.

Case Study: Assessing Compound Selectivity & Potency Across Delta Set M Assays

 

Sunitinib


Sunitinib

Erlotinib


Erlotinib

Dasatinib


Dasatinib
Kd values < 3 µM for three FDA-approved kinase inhibitors across the 174 kinases not available from the next leading provider.

 

scanUNIQUE™, Delta Set M - 174 Kinases
AAK1ACVR1ACVR2A
ACVR2BACVRL1ADCK3
ADCK4AMPK-alpha1AMPK-alpha2
ANKK1ASK2AURKC
BIKEBLKBMPR1A
BMPR1BBMPR2BRAF
BUB1CAMK1GCAMK2A
CAMKK1CAMKK2CASK
CDC2L1CDC2L2CDC2L5
CDK11CDK4-cyclinD1CDK8
CDKL1CDKL2CDKL3
CDKL5CITCLK1
CLK4CSNK1A1CSNK1A1L
CSNK1ECTKDCAMKL1
DCAMKL3DDR1DLK
DMPK2DRAK2DYRK1A
DYRK1BEIF2AK1EPHA6
EPHB6ERBB2ERBB3
ERK3ERK4ERK5
ERK8ERN1GAK
GCN2(Kin.Dom.2,S808G)GRK1GRK4
HIPK4HPK1HUNK
ICKIKK-epsilonIRAK3
JAK1(JH1domain-catalytic)JAK1(JH2domain-pseudokinase)LATS1
LATS2LIMK2LRRK2
LTKLZKMAK
MAP3K1MAP3K15MAP3K2
MAP3K3MAP3K4MAP4K3
MAP4K4MAP4K5MARK3
MARK4MAST1MEK2
MEK3MEK4MEK5
MKNK1MLCKMLK2
MLK3MST4MYLK2
MYLK4MYO3AMYO3B
NDR1NDR2NEK1
NEK4NEK5NEK9
NIM1OSR1PAK1
PCTK1PCTK2PCTK3
PFTAIRE2PFTK1PHKG1
PIK3C2BPIK3C2GPIK3CA
PIK4CBPIP5K1APIP5K1C
PIP5K2BPIP5K2CPKAC-beta
PKMYT1PKN1PLK4
PRKD3PRKG2PRKR
PRP4QSKRIOK1
RIOK2RIOK3RIPK1
RIPK4RIPK5SBK1
SgK110SIK2SLK
SNARKSNRKSRMS
STK16STK35STK36
STK39TESK1TGFBR1
TGFBR2TIE1TLK1
TNIKTNK1TNNI3K
TRKCTRPM6TTK
TYK2(JH1domain-catalytic)TYK2(JH2domain-pseudokinase)ULK1
WEE1WEE2WNK1
YANK1YANK2YANK3
YSK1YSK4ZAK