ABL1(M351T)-phosphorylated
KINASE INFORMATION
Kinase Name
c-abl oncogene 1, receptor tyrosine kinase
Entrez Gene Symbol
ABL1
Entrez Gene ID
25
Aliases
ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl
Kinase Group
TK
Species
Human
Phosphorylated
yes
PROTEIN INFORMATION
Accession #
NP_005148.2
Kinase Construct
Partial Length
Kinase Form
Mutation (M351T)
Mutation Relevance
Mutation confers imatinib-resistance in chronic myeloid leukemia (CML).
Mutation References
Blood.
100, 1014-1018 (2002)
Expression System
Mammalian
ASSAY INFORMATION
Average Z’ Value
0.77
Panel
scanELECT; scanMAX; scanTK;
REFERENCE INHIBITOR INFORMATION
Compound
Kd